What's autoimmune hepatitis?
Autoimmune hepatitis is a chronic inflammatory liver disease in which the immune system attacks the liver, marked by high immunoglobulin levels and circulating autoantibodies, and more common in women.
| Features mapped | 5 |
|---|---|
| Treatments mapped | 1 |
| Published sources | 4 |
| Last reviewed | 2026-08-04 |
Signs and symptoms
Elevated circulating hepatic transaminase concentration
Raised liver enzymes (transaminases) in the blood are a typical sign of active autoimmune hepatitis.
Antinuclear antibody positivity
Many people with autoimmune hepatitis have antinuclear antibodies (ANA), a self-directed antibody, detectable in the blood.
Cirrhosis
Over time, autoimmune hepatitis can progress to cirrhosis, scarring of the liver.
Jaundice
Jaundice, a yellowing of the skin and eyes, can occur in autoimmune hepatitis.
Increased circulating IgG concentration
Blood levels of immunoglobulin G (IgG) antibodies are typically raised in autoimmune hepatitis.
Treatment and management
What the research describes, not a recommendation. Treatment decisions belong with your clinician.
This covers treatments that appear in the published research mapped here. Investigational and experimental therapies are not included, so their absence is a boundary of this map, not a sign they do not exist.
corticosteroids
Corticosteroids such as prednisone are the mainstay treatment for autoimmune hepatitis and reduce raised transaminases and liver inflammation.
Used to help with: Elevated circulating hepatic transaminase concentration.
“Both ADSC and prednisone monotherapies significantly reduced serum transaminases (ALT, AST, ALP, TBIL) and hepatic inflammation compared with untreated controls.”
How to read the evidence labels
Where this comes from
This guide is built from 4 published source(s). Every claim above links back to one of them. Click any source ID to read the original on PubMed.
Take it further
Printed, source-linked documents built from this condition's graph — ready to bring to an appointment or attach to a coverage request. Every claim carries its published source, the same as this guide.